NFL Week 15 kicks off with a NFC West rivalry game between and the host and and the red-hot on Thursday Night Football. (ankle) is out for San Francisco, while will be available for Seattle -- factors that should be considered when building your DFS lineups and NFL DFS stacks for Seahawks vs. 49ers on TNF. With Samuel out, should fellow 49ers star be considered a must-start option in your TNF Showdown NFL DFS strategy? Or would it make sense to look at the other running backs, tight ends, wide receivers, or a D/ST in the TNF NFL DFS player pool? , , , , and all project to be Zion Williamson Jersey impact cla sic and showdown NFL DFS picks for Thursday Night Football.Before making any Thursday NFL DFS picks for 49ers vs. Seahawks on sites like DraftKings and FanDuel of your own, .Kaylor is an NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor has covered the NFL and for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.Kaylor has been spot-on all season, hitting on epic NFL DFS picks like (4-102-1), ( George Hill Jersey 12-148-3, 6-106-1, 7-92-1), (7-101-1, 5-131-1), (23-113-1, 23-101-2), (8-87-1), Deebo Samuel (6-115-1) (14-122), (7-25-4, 10-106), (3-124-2), (179-1-1, 82-1), (132-2), (228-4), and (7-61-1). Anyone who has followed his picks is way up.Now, Kaylor has turned his attention to Seahawks vs. 49ers on Thursday Night Football Week 15 and locked in his top daily picks. . One of Kaylor's favorite DFS picks for the 49ers vs. Seahawks showdown Solomon Hill Jersey slate on Thursday Night Football is San Francisco running back Christian McCaffrey. The former Stanford star has fit into Kyle Shanahan's offense seamle sly, and is having one of the most productive seasons of his already impre sive NFL career. Entering Week 15, McCaffrey has 174 carries for 819 yards and five touchdowns to go alone with 68 receptions for 593 yards and four touchdowns, giving him a chance to go over 2,000 total offensive yards for the second time in his profe sional career. With Deebo Samuel out on Thursday night, Kaylor is expecting an increased workload for McCaffrey on TNF."Christian McCaffrey is a must-start player in most Showdown slates on both FanDuel and DraftKings, but I am particularly high on him in Week 15 against the Seahawks. San Francisco will be without wide Sindarius Thornwell Jersey receiver Deebo Samuel, which alone should open up a few more touches for McCaffrey. Couple that with Seattle ranking second to last in the league rushing yards allowed per game (160.5) and you have the makings of a monster NFL DFS performance for McCaffrey on TNF. I am projecting around 20 touches for 125+ total yards and a touchdown for McCaffrey on Thursday night New Orleans Pelicans T-Shirts ," Kaylor told SportsLine. .Kaylor is also targeting another undervalued option that could explode for huge numbers for Thursday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. . So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Thursday Night Football? And which under-the-radar DFS picks offer huge value? , and find out.