Take one Zenegra 50 mg tablet with a full glass of water. It can be taken with or without food. Avoid consuming grapefruit or grapefruit juice while using Zenegra 50 mg, as it can interact with Sildenafil and affect its effectiveness. Consult a healthcare professional before starting Zenegra 50 mg or any ED medication. They can assess your health status, medications, and potential interactions. https://www.genericday.com/zenegra-50-mg.html